Traumatic Brain injury

Repetitive Traumatic Brain Injury (TBI)

We are using novel imaging techniques in pre-clinical mild TBI models in an effort to accurately quantify mechanistic changes in the brain associated with repetitive blunt and blast brain trauma.

Effects of Traumatic Brain Injury

Effect of Traumatic Brain Injury (TBI) on Perivascular Spaces (PVS)

TM3 is studying the effect of mild traumatic brain injuries (TBI) on the perivascular spaces (PVS) in the brain and their subsequent effect on waste clearance. There have been studies conducted independently that study the adverse effects of TBI on PVS as well as PVS being directly implicated in waste clearance of molecules such as Amyloid-Beta or other neurodegenerative-inducing molecules. This study seeks to combine prior research into a novel study that begins to reveal the detrimental effects of TBI on the human brain.